She is fluent in Kannada, Sindhi, Hindi, English. She studied in Jai Hind College, Mumbai where her older sister Deepa studied as well.
Her mother is the vice-principal of the junior college section of Jai Hind College.
Preeti Jhangiani first appeared in a Rajshri Productions' Music Album Yeh Hai Prem opposite Abbas, this made them as well as the koala bear symbol - famous. Thereafter she has appeared in Nirma Sandal soap ads.
Her first film was in Malayalam which was called Mazhavillu. She made her Bollywood debut in 2000 with Mohabbatein. The film was a hit and started her film career. Her next hit was the comedy Awara Paagal Deewana.
She has also acted in Punjabi films such as Sajna ve Sajna. She married actor Parvin Dabas on 23 March 2008. She lives in Bandra, Mumbai.